Tag Archives: diabetic retinopathy

Taxifolin and diabetic retinopathy

Hiperglycaemia and oxidative stress activate a few bad trails, such as the poliol trail, kinases protein C (PKC), final products of advanced glycation of proteins (AGEs) and heksozoamin that which are responsible for the pathological changes in the blood microcirculation and retinal microcirculation and nerve cells and glial.

Oxidative stress in diabetes is the result of high concentrations of glucose and fatty acids. This plays an important role in the pathogenesis of diabetes and its complications. Its pathogenic activity involves, inter alia, on the inhibition of the synthesis of insulin in pancreatic beta cells and inhibition of signal transmission in target cells with an insulinic. This action contributes to the development of insulin resistance and induce changes in the walls of the blood vessels leading to the complications of diabetes.

Complications include damage to the retina, called as diabetic retinopathy. Diabetic retinopathy is formed as a result of damage to the small blood vessels that nourish the retina, leading to a brain hemorrhage in the eyeball. Increasingly scientists carry out research on the effectiveness of the use of antioxidants, which may have a potential impact on metabolic changes in diabetic retinopathy. In view of the good prognostic antioxidant properties dihydroquercetin (taxifolin) it has been decided to carry out control tests in the field of health support blood vessels in diabetics.

220px-Eye_disease_simulation,_normal_vision
1 / first picture shows the normal vision photo Source: Internet
Eye_disease_simulation,_diabetic_retinopathy
Eye_disease_simulation,_diabetic_retinopathy Source photo: internet

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