Radioprotective properties of taxifolin

People who have to deal with cancer often touches on the problem of complications after irradiation.
Under the influence of radiation damage is, first and foremost, blood vessels and connective tissue. After irradiation can also experience additional symptoms that may occur at the same time, these include among others. fatigue, general weakness, reduce the natural resistance of the organism, anorexia, depression, changes in activity in the blood (reduction in the number of white blood cells and platelets), skin reactions, redness, hair loss on the scalp irradiated, only in the case of brain tumors, mucosal reactions in the oral cavity, pharynx, larynx, nasal cavities when irradiated tumors of the head and neck, skin reactions, respiratory and heart (late) in the irradiated organ chest, skin reactions and entero-bullous when irradiated with a range of reactions and belly of the rectum, the vagina, the vulva with pelvic irradiated.

In some cases, especially when irradiated is the thorax may cause damage to the heart muscle, especially when applied to high doses of radiation for cancer of the lungs, lymph nodes in the mediastinum, covering the area between the lungs in close to the heart.

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Taxifolin and diabetic retinopathy

Hiperglycaemia and oxidative stress activate a few bad trails, such as the poliol trail, kinases protein C (PKC), final products of advanced glycation of proteins (AGEs) and heksozoamin that which are responsible for the pathological changes in the blood microcirculation and retinal microcirculation and nerve cells and glial.

Oxidative stress in diabetes is the result of high concentrations of glucose and fatty acids. This plays an important role in the pathogenesis of diabetes and its complications. Its pathogenic activity involves, inter alia, on the inhibition of the synthesis of insulin in pancreatic beta cells and inhibition of signal transmission in target cells with an insulinic. This action contributes to the development of insulin resistance and induce changes in the walls of the blood vessels leading to the complications of diabetes.

Complications include damage to the retina, called as diabetic retinopathy. Diabetic retinopathy is formed as a result of damage to the small blood vessels that nourish the retina, leading to a brain hemorrhage in the eyeball. Increasingly scientists carry out research on the effectiveness of the use of antioxidants, which may have a potential impact on metabolic changes in diabetic retinopathy. In view of the good prognostic antioxidant properties dihydroquercetin (taxifolin) it has been decided to carry out control tests in the field of health support blood vessels in diabetics.

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1 / first picture shows the normal vision photo Source: Internet
Eye_disease_simulation,_diabetic_retinopathy
Eye_disease_simulation,_diabetic_retinopathy Source photo: internet

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Does diabetes lead to damage of the blood vessels?

Complications of diabetes are most commonly associated with damaged blood vessels, atherosclerosis, coronary artery disease, damage to the retina of the eye and kidney disease. The disease can last for years before being detected, which is very dangerous, as even a small increase in blood sugar levels can damage the blood vessels and accelerate atherosclerotic processes. Therefore, diabetes should not be underestimated, even if this is the initial stage of development of this disease, because it contributes to the development of atherosclerosis, and this is the most common cause of death. High blood sugar levels helps the formation of atherosclerotic plaques, gradually tapered diameter of the coronary arteries.

widoczne zmiany miażdżycowe aorty
visible atherosclerotic lesions of the aorta Source photo: internet

A change in the metabolism of the heart cells causes an increased need for nutrients with limited blood supply. This is the cause of myocardial ischemia, which can lead to heart attack, heart failure and sudden death of a heart. The risk of heart attack in hospitalised patients with diabetes is very large. Diabetics must therefore pay particular attention to the control of the General State of health and rapid response in the event of distressing symptoms.

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